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agent model), there are prostaglandins analoguesethanol model (Robert, 1979) relationships, NSAIDsacetic acid model (Okabe and Amagase, 2005) relationships, dopamine agonistscysteamine model (Selye and Szabo, 1973) relationships, and H 2 blockerscysteamine model (Selye and Szabo, 1973) relationships