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In these studies, ALA showed no influence on the activity of GR

Mass spectrometry was used to determine the changes in pyruvate, malate, phosphoenolpyruvate (PEP), and glucose levels following MDSA or EA treatment (Fig

Abbreviations BMP2: Bone morphogenic protein BC: Bone crest CEJ: Cementoenamel junction ELISA: Enzyme-linked immunosorbent assay Ep: Experimental periodontitis FBC: Furcal bone crest FR: Furcation roof GSH: Glutathione IL: Interleukin MDA: Malondialdehyde MDP: Microbial dental plaques MMP: Matrix metalloproteinases MSM: Methylsulfonylmethane PGE 2 : Prostaglandin E 2 RANKL: Receptor nuclear factor kappa B ligand OPG: Osteoprotegerin OSI: Oxidative stress index TAS: Total antioxidant status TNF-: Tumor necrosis factor-alpha TOS: Total oxidant status References Tonetti MS, Greenwell H, Kornman KS

Animal models suggest that reductions in glutathione synthesis capacity in mid-life may precede later elevations in reactive oxygen species (ROS) and oxidative damage