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doi:10.1073/pnas.94.5.1967 19

Additionally, mRNA is a minimal genetic vector, which can help evade anti-vector immunity and therefore, enable repeated administration (McKinlay et al., 2018)

Fgl2 -/- mice showed significant reduction of NETs levels and hepatic fibrin deposition, along with decreased complement and coagulation factors, including TAT, fibrinogen, C3a and C5a expression