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Cold acclimation induces zonal heterogeneity in gluconeogenic responses to glucagon in rat liver lobule

In addition, IGF-1 LR3 may enhance tumor stem cell characteristics by inducing epithelial mesenchymal transition (EMT), leading to increased chemotherapy resistance and recurrence risk

In vitro studies apply Selank to cultured neuronal cells and immune cells to characterize direct cellular effects independent of whole-organism pharmacokinetics, providing mechanistic data on receptor interactions and intracellular signaling responses