Supplements and Their Role in Increasing Glutathione Levels: To ensure optimal levels, some individuals turn to glutathione supplements
Timestamps 00:00 Cold open: 200 years of menopause medicine 03:23 Welcome and roadmap 04:20 The HPG axis, follicles, and the FSH lag 09:11 STRAW+10 staging and the timing of perimenopause 13:47 Austin: the 49-year-old with a hormone panel 20:00 Loraine: the OB-GYN workup 28:00 Symptom attribution: what menopause actually causes 33:46 Austin: the all-estrogen patient 37:58 VMS duration and the KNDy mechanism (Avis, SKYLIGHT) 43:53 Austin: who actually gets fezolinetant 47:22 The WHI 24-year correction (Manson, Chlebowski, Boardman) 01:00:15 Modern prescribing today 01:06:52 Where the menopause-content space gets it right and wrong 01:11:50 Testosterone, compounded bioidenticals, and DUTCH panels 01:24:13 Takeaways What we cover The HPG axis and the estrogen shield: what is happening across the 35-year reproductive era and what changes at perimenopause
Use a 1.0 ml syringe when your dose genuinely requires it
Training split suggestions : 45x/week upper/lower or push/pull/legs split Emphasize progressive overload: 612 rep range, 23 RIR (reps in reserve) Include joint-friendly movement selection (controlled eccentrics, proper warm-up) Use metabolic finishers sparingly if appetite is already elevated Recovery enhancements : MK-677 enables more frequent training, but be cautious with overreaching Track HRV or resting heart rate for signs of central fatigue Incorporate active recovery: walking, mobility, sauna, light cardio Supplement Support To amplify your results and support recovery during a cycle: DHEA (100 mg/day) : Supports hormonal recovery, especially in natural users ZMT : Promotes deeper sleep, cortisol control, and natural test support Greens + Reds : Enhances gut health, detox support, and micronutrient absorption Krill Oil : Supports inflammation reduction, lipid health, and cognitive recovery The Swole Kitchen Nutrition Coaching : Get macro-adjustments, habit tracking, and weekly check-ins for real progress Post-Cycle Considerations for MK-677 Unlike anabolic steroids or suppressive SARMs, MK-677 does not shut down testosterone production or suppress the hypothalamic-pituitary-gonadal (HPG) axis , meaning traditional post-cycle therapy (PCT) is not required when MK-677 is used on its own
