melanotic lupus erythematosus Blaschkoid cutaneous with “melanocytic nests” - Bigotto - 2024 - Journal of Cutaneous Pathology Generalized facial pigmentation: An uncommon

GLP-1 medications slow gastric emptying, which can reduce the absorption of oral medications

The PI3K/AKT/mTOR pathway was recently showed to reduce oxidative stress and promote cell survival of breast epithelial cells segregated from the ECM by strengthening flux through the oxidative PPP (195) PIK3CA mutation, which leads to increased PI3K activity, is the most common somatic mutation in breast cancer, and 36% of patients with HR+/HER2- breast cancer are PIK3CA mutated (196)

By promoting STAT3 activation, IL6 fosters macrophage survival and M2 marker expression, while also driving fibroblastmyofibroblast transition

Its a fantastic way to achieve a youthful, rejuvenated appearance just in time for spring