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Among microbiota-based interventions, FMT exerts the most extensive metabolic effects, but the precise outcome heavily relies on the donors microbial profile

Restricting cysteine, depleting GSH, or inhibiting GPX4 can increase phospholipid peroxidation in responsive cells, but sensitivity also depends on lipid composition, iron metabolism, parallel antioxidant systems, and tissue context (Jiang et al., 2021)

There are many causes that may increase probability of breast cancer development, such as DNA damage and mutations

This review systematically describes the metabolic pathways of ferroptosis and summarizes the mechanisms of action of natural and synthetic small-molecule inhibitors of ferroptosis as well as their applications in disease