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this process leads to the formation of lipid peroxides, such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), which are highly reactive and cause cellular damage and inflammation ( Protein oxidation plays a critical role in the development of IBD ( HP1021 as a redox switch protein identified in Helicobacter pylori

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Nature 427 , 537541 (2004)

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