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10.3390/cancers12040970 19 CamioloG.BarbatoA.GiallongoC.VicarioN.RomanoA.ParrinelloN

Because cardiomyocytes are terminal differentiated cells, their loss in heart failure is irreversible, therefore, preventing cardiomyocyte hypertrophy and death is of great physiological significance for maintaining heart function and delaying heart failure