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doi: 10.1104/pp.16.00648 127 RouhierN.JacquotJ

This occurs because solid tumors generally exist in hypoxic conditions, marked by diminished oxygen and glucose levels, creating a conducive environment for CSCs to endure and evade cell death

MTHFR, a key enzyme in folate metabolism, has been widely studied in relation to neural tube defects and hypertension, but its role in colorectal cancer remains underexplored