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L-carnitine IV therapy is generally safe when administered by qualified healthcare professionals

Impact of the COVID-19 Pandemic on the Wellness of Faculty and Trainees in Surgery, 2021

Characterized by motor deficits and cognitive decline with some psychiatric symptoms such as depression and anxiety, HD is mainly due to abnormal duplication of CAG nucleotides of the gene encoding the Huntington protein, which eventually produces abnormal protein polyglutamine (polyQ) and largely accumulates in the neurons of basal ganglia (caudate-putamen), and finally cortico-striatal dysfunction

We confirmed that FLT3i decreased the protein expression of these lipid metabolism regulators in FLT3-mutant AML PDX samples and AML cell lines ( Figure 1H-I and S3C-D )