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Being a -butyrobetaine analogue, meldonium inhibits the activity of -butyrobetaine hydroxylase, the enzyme that catalyses the formation of l-carnitine 23 , and the l-carnitine renal re-absorption 24

Numerous studies using rodent models have reported various events occurring in the dorsal root ganglia (DRG) and the spinal cord after chemotherapy, such as ion channel dysfunction, axonal degeneration of the sciatic nerve, impaired mitochondrial function, and excessive oxidative stress

An alternative possibility is that humans have capacity for the same level of skill as in faces, but we see low odour identification rates because, again, we tend to test in ODD populations where people do not have sufficient opportunity to learn or maintain skills in olfactory perception (Roberts et al., Reference Roberts, Havlek and Schaal2020a)