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Similarly in Italy, youth e-cigarette users substantially increased from 0% in 2010 to 7.4% in 2014 and to 17.5% in 2018, and exclusive e-cigarette users recorded an almost three-fold significant increase from 2.9% in 2014 to 8.2% in 2018 (16)

They were usually put near the bathrooms of bars and restaurants, since these lavatories were often so small that they lacked the amenities that many of todays public restrooms have (like, say, sinks and mirrors)

First, the absence of certain covariates in the analyses may have led to residual confounding

Others find the experience harsh, overwhelming, or just plain unpleasant