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The reported increases in total glutathione and GSH:GSSG in tobacco and Arabidopsis overexpressor lines could be partly related to the need for enhanced GSH to support increased DHAR activity (Chen and Gallie, Glutathione status was also assessed in tobacco lines overexpressing a GST with GSH peroxidase activity (Roxas et al., 4), is able to decrease the reduction state of glutathione in vivo

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Mania In placebo-controlled clinical trials of acute mania, patients were dosed to clinical response with trough plasma concentrations between 50 and 125 g/mL (See DOSAGE AND ADMINISTRATION)

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