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Much of the purported clinical utility is derived from anecdotal accounts or small, uncontrolled series, rather than from robust randomized trials

Overall, the evidence supports the use of B12, on its own or in addition to other supplements, for the reduction of homocysteine levels

Many patients with diagnosed deficiency find their symptoms significantly improve after targeted supplementation, with over 90% reporting positive changes within a few months of treatment

PlexusDx supports your full therapy protocol through licensed 503A compounding pharmacies, and your clinical team can help select the B12 form and dose that fits your individual needs