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J Rheum Dis 2011;14:122 2

The antioxidant power of the intestine was compromised due to inhibition of key antioxidant enzymes and decreased reduced glutathione levels which led to impaired free radical quenching and metal-reducing ability

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Patients on GLP-1 therapy often remain in a low-grade inflammatory state during the active weight loss phase, which can slow the very tissue remodelling that would otherwise benefit from reduced adiposity