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GHK-Cu works differently-its a non-hormonal topical peptide

doi: 10.1007/s40257-018-0404-3 405 JiangWNiBLiuZLiuXXieWWuIXet al

Aviram M, Dornfeld L

Evidence from a murine model of acetaminophen-induced acute liver injury, supported by ex vivo studies with macrophages, suggests that neutrophil-derived ROS can promote metabolic reprogramming in macrophages by activating AMPK via the Ca 2+ -CaMKK pathway