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doi: 10.1021/acsomega.3c01910 172 SinghR.HanoC.NathG.SharmaB

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For instance, during critical windows of brain maturation, the combined administration of ketamine with thiopental or propofol significantly amplifies neuronal cell death in neonatal animals and results in enduring functional impairments in adulthood, whereas the administration of these agents individually tends to produce only modest neurodevelopmental effects (Fredriksson et al