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Wearing the aligners for the recommended 20-22 hours per day is crucial for efficient treatment progress

The abnormal aggregation and deposition of A peptides are considered pivotal in the pathogenesis of AD, contributing to neuronal damage, synaptic dysfunction, and a progressive decline in cognitive abilities [79]

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These studies have shown that NOR is an effective monomer drug for the treatment of RA, which can play a role by anti-inflammation, immune regulation, promoting synovial cell apoptosis, inhibiting osteoclast differentiation and synovial angiogenesis, and regulating lipid metabolism