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Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma ScienceDirect Pro Oxidant Auranofin and Glutathione Depleting Combination Unveils Synergistic Lethality in Glioblastoma Cells with Aberrant Epidermal Growth Factor Receptor Expression nadph increase and glutathione levels u87 cells NADPH oxidase activity antioxidant machinery in CLL cells. (A) Blocking glutathione regeneration: Inorganic NADPH U87 cells do not swell following the application of 100, 10 ns pulses Download Scientific Diagram
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