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For instance, the curcumin nanoparticles with higher hydrophilicity achieved by loading into sophorolipid micelles had an appreciably higher bioavailability than that of free curcumin crystals (Peng et al., 2018)

Surprisingly, studies investigating a direct antiviral role for ROS in macrophages, e.g., by induction of oxidative damage to the viral genome [297] or by modulation of autophagic pathways needed for genome replication, packaging or release of viral particles [298,299,300,301] are largely missing