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Nursing & Patient Tips and Precautions Vaccinating B by injection is generally safe, but nurses and patients should note: Injection technique: Use standard IM technique

Increasing the dose does not appear to increase benefits and may only add unnecessary risk

Furthermore, given that the patients with high pre-treatment CD38 levels on MM cells have a better response to Daratumumab monotherapy, high CD38 expression on MM cells seems satisfactory to maximize the clinical efficacy such as the combination treatment of CD16F158V CD38 low NK cells and Daratumumab [120]