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11:e168287

The dosages utilized for skin whitening therapy have no adverse side effects

Metabolic treatments in ALS Given that defects in energy metabolism are evident in ALS, addressing these disturbances is a reasonable approach to improve quality of life and prolong survival in patients with ALS

This sample size is consistent with prior mechanistic studies and the 3R principles [52, 53], although the relatively small cohort remains a limitation and should be expanded in future work