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Based on the above shortcomings, we have summarized the compounds that have been studied for structural modification, including shikonin, curcumin, oleanolic acid, alepterolic acid, neo-tanshinlactone and genistein, aiming to provide ideas for structural modification of natural products (Fig

and the sequence homologous to the template polynucleotide can be x bases long, wherein x is an integer between 10 and 30, or, between 2 and 20

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