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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Gomes AP, et al

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Anything with an -OH is an alcohol in the chemistry sense, so things like sugar are super alcoholic

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More importantly, Nrf2 gene knockout inhibited the antifibrotic effect of AS-IV by downregulating the p-Smad3L/PAI-1 pathway and upregulating the p-Smad3C/p21 pathway (Yang, 2022)

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However, it is important to note that curcumin has also been identified as a PAINS, exhibiting behaviors such as redox cycling, metal chelation, aggregation, and fluorescence interference that can artificially inflate its apparent bioactivity in vitro (Nelson et al., 2017)

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