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In general, apoB-containing lipoproteins, such as LDL and chylomicron remnants, link to plaque buildup in the arteries (not good).[ref] Luteolin acts on HNF4, a nuclear transcription factor, in regulating the secretion of apolipoprotein B (apo B) containing lipoproteins.[ref] This means that luteolin is acting upstream of the production of cholesterol in the liver regulating the production of cholesterol

It was unveiled in 1983 by the late King Olav

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Water is used instead of phosphate-buffered saline (PBS), because while PBS has comparable osmolarity and buffering capacity to plasma, it also contains salts and other components that could potentially interfere with the detection and quantification of metabolites