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However, during inflammation, pro-inflammatory cytokines such as IFN-, IL-1, IL-12, tumor necrosis factor- (TNF-), and bacterial lipopolysaccharides (LPS) induce the expression of iNOS (Qureshi, 2003

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Key proteins associated with these pathways, including p65, p60, STAT3, Jak1, and p38, show significant inhibition in the Fat-1 group

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