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Unlike TRT, enclomiphene preserves LH, FSH, and spermatogenesis, making it the primary hormonal option for men who want to optimize testosterone without sacrificing fertility

The proteins synthesized may be dysfunctional or excessively immunogenic, thereby triggering autoimmunity or other pathological effects (e.g., cellular dysfunction or disease)

Jarvis JN, Lawrence DS, Meya DB, Kagimu E, Kasibante J, Mpoza E, Rutakingirwa MK, Ssebambulidde K, Tugume L, Rhein J, Boulware DR, Mwandumba HC, Moyo M, Mzinganjira H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Harrison TS (2022) Single-dose liposomal amphotericin B treatment for cryptococcal meningitis

It is equally important to be precise about where each compound sits on the evidence ladder