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Anoxia also induces insulin resistance and through HIF-1 activates the Cori cycle

Even though the cause of fatigue in PBC remains unclear, it may be related to dysfunction of either the corticotrophin-releasing hormone or serotonergic neurotransmitter systems [152]

Passaia G, Queval G, Bai J, Margis-Pinheiro M, Foyer CH (2014) The effects of redox controls mediated by glutathione peroxidases on root architecture in Arabidopsis thaliana

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