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(2018) and Elsayed et al

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For this reason, EASL guidelines suggest prudentially an individualized follow-up every three years for asymptomatic family members and first-degree relatives of heterozygous parents with severe MDR3 deficiency, even if they have normal laboratory values and no signs of advanced liver fibrosis or gallstone disease [68]

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doi: 10.1038/ajg.2011.67 5 PerrottaCPellegrinoPMoroniEDe PalmaCCerviaDDanelliPet al

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