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Primary sequence analysis indicates GDAP1 contains two GST domains: a putative glutathione (GSH) binding domain (called the G-site), and an H-site responsible for recognizing hydrophobic substrates in canonical GSTs (Awasthi et al., 1993

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This Review aims to provide an evidence-based synthesis of the main nutritional strategies used in the treatment of T2DM, with a focus on their underlying mechanisms, clinical efficacy and potential for sustainable long-term implementation