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Statistical Analysis Metabolite concentrations were normalized to sample volume utilized for extraction and rescaled to set the median equal to 1

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Because sperm cells have mitochondria and walls containing high levels of polyunsaturated fat, they are especially vulnerable to oxidative stress

This conceptual framework provides an important biological basis for understanding how natural plant-derived compounds may improve lipid metabolic homeostasis through modulation of the gut microbiota (Figure 1)