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plantarum can improve lipid oxidation by increasing the mRNA expression of lipid oxidation genes, including CPT1, ACOX1, and MCAD, and reduce lipid synthesis by activating the SIRT1-PGC-1 alpha pathway, leading to reduction of fat accumulation (Kwon et al., 2020)

Equal amount of each fraction was mixed with 4x Laemmli Sample Buffer (Bio-Rad) and resolved on SDS-PAGE followed by immunoblot analysis

Overall, these findings place NAC as a powerful co-adjuvant tool to enhance the effectiveness of MAL-PDT treatment for cSCC by preventing the development of resistance