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The FSP1/CoQ10 pathway suppresses lipid peroxidation and ferroptosis by utilizing FSP1 to regenerate reduced CoQ10, a lipophilic radical-trapping agent, via NADPH

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This review discusses ADC linker design strategies , covering cleavable and non-cleavable linker types, functional groups for antibody conjugation, self-immolative spacers, and hydrophilic modifications