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Description

The assembly and activation of inflammasome complexes in response to intracellular and extracellular pathological signals lead to the activation of inflammatory caspases 1, 4, 5, and 11, ultimately causing mitochondrial outer membrane permeability (MOMP) and subsequent cell death (102)

doi: 10.1196/annals.1316.057

Abbreviations pCBs: phytocannabinoids

Katsiampoura A, Raghav K, Jiang ZQ, Menter DG, Varkaris A, Morelli MP, Manuel S, Wu J, Sorokin AV, Rizi BS, Bristow C, Tian F, Airhart S, Cheng M, Broom BM, Morris J, Overman MJ, Powis G, Kopetz S