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Orhan F, Parlak KU, Tabay D, Bozar S (2023) Alleviation of the cadmium toxicity by application of a microbial derived compound, ectoine

The reduced activity of the signal molecule AI-2 at a later stage may be related to the unstable and easily decomposed character of the signal molecule AI-2 (Chen et al., 2002)

But the major limitation of the use of flavonoids is the adverse effects associated with their consumption in high doses, including necroptosis, apoptosis, cardiac dysfunction, and neurotoxic side effect (Satari et al., 2021)