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Molecular integration of incretin and glucocorticoid action reverses immunometabolic dysfunction and obesity

In contrast, 55% of PD patients had Lewy microsomes in the mucosa and submucosa, with the detection of Lewy fibers in submucosal biopsies of the rectum as well as the ascending and descending colon in 2365% of PD patients

stiffness and resistance to limb movement caused by increased muscle tone and/or an excessive and continuous contraction of muscles, which may be uniform (lead-pipe rigidity) or ratchety (cogwheel rigidity), and which may be associated with joint pain

MW and DG conceived and designed the study