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The mechanisms behind these associations suggest that oral bacteria and their metabolites can enter the bloodstream through oral epithelial barriers or via direct interactions with the respiratory and digestive systems, thereby influencing systemic health [33,34,35]

Regulations also many times come as the result of a long, tedious process in which special interest groups can exert considerable influence, and industries having a significant financial interest in the continued use of a particular product may be quite successful in limiting regulatory controls