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Its substrate site-targeting mechanism inhibiting NNMT at the nicotinamide binding site provides selectivity over related methyltransferases and other enzymes in the NAD salvage pathway, making it a precise tool compound for studying NNMT-specific enzymatic activity in controlled laboratory systems

doi:10.1007/978-3-7643-8340-4_6 [33] Collins JF, Prohaska JR, Knutson MD

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