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A recent study showed that the HSV-1 host/pathogen interactome is highly concentrated in susceptibility genes for neurological disorders, primarily for MS, with enrichment values at 4-fold, suggesting that HSV-1 may contribute to several diseases in a gene-dependent manner by modulating essential pathways involved in the onset or severity of this neurodegenerative disease (Carter, On the other hand, microorganisms may also contribute to the pathogenesis of MS by inducing the activation and clonal expansion of self-reactive lymphocytes through molecular mimicry (Wucherpfennig and Strominger, 1995)

The U1Grx1roGFP2 cells were challenged with various concentrations of H 2 O 2 for 2 min, and the sensor response was quantified

Starting conservatively accounts for this uncertainty

Abstract Contextualisation of the new type of cell death called ferroptosis opened a completely new avenue for the development of anti-cancer therapies