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Regulatory T cells (Tregs) present significant therapeutic potential for autoimmune liver diseases and transplantation tolerance

Rifabutin-Based triple therapy (RHB-105) for Helicobacter pylori eradication: A double-blind, randomized, controlled trial

The resulting decrease in the -KG/succinate ratio inhibits the activity of -KG-dependent dioxygenases, leading to a reduction in 5-hydroxymethylcytosine (5hmC) level, epigenetic dysregulation, and ultimately driving tumor cell dedifferentiation and enhanced adaptability [150]