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10.1016/j.immuni.2013.10.022 34 FukuiS.MizunoM.TawadaM.SuzukiY.KojimaH.MatsukawaY.et al (2023)

Modulation of the in situ activity of tissue transglutaminase by calcium and GTP

Research shows that high-lutein sources like spinach are proven to help decrease eye-related degeneration and improve visual acuity

However, concerns regarding gene dosage will have to be considered with gene therapy and modulation of frataxin expression since frataxin overexpression was reported to be toxic in several models (Navarro et al., 2011