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Access this article Similar content being viewed by others References Alanazi AM, Mostafa GA, Al-Badr AA

The indirect antioxidant activity of glutathione is demonstrated by glutathione peroxidase (GPx), which uses glutathione as a reducing agent to catalyze the reduction of H 2 O 2, or organic hydroperoxides to water

This can cause the estrogen metabolites to be reabsorbed from the intestines and go back into circulation.[ref] Calcium D-glucarate can suppress the beta-glucuronidase activity in the gut, thus increasing the number of estrogen metabolites that are excreted.[ref] Hormone Replacement Therapy: Hormone replacement therapy (HRT) in menopause is the replacement of naturally declining estrogen and progesterone levels with either synthetic or bioidentical hormones