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Furthermore, Nrf2 activators reduce the extent of neuronal death caused by iron overload, most likely by regulating genes associated with iron metabolism and the synthesis of antioxidants that protect cells from oxidative stress and ferroptosis [48, 49]

Day 2: two injections of morphine (15 mg/kg,IV)

The arrow in the diagram to the right shows where the glutathione is located in the liposome.* Liposomes penetrate mucosal tissues allowing for rapid release into the blood stream