The 2010s introduced gene-expression analysis: data generated through the Broad Institute's Connectivity Map indicated that GHK exposure modulated expression of 4,192 of the 13,424 human genes assayed, with approximately equal up- and down-regulation across stress-response, inflammation, and tissue-repair pathways [2]
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Whereas dietary glutamine supplementation in infants leads to higher plasma levels of this AA (80, 81), plasma levels of glutamate are largely unaffected by dietary glutamate (82, 83)
doi: 10.1016/j.celrep.2019.02.063 148 JacobFSalinasRDZhangDYNguyenPTTSchnollJGWongSZHet al
