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Description

Mitochondrial alterations near amyloid plaques in an Alzheimer's disease mouse model

The enzymatic activity in the range 0.10.4 U/mL can be measured using a simple colorimetric reader

2015;7:a020412a020412

In this context, acetyl-CoA acts as a metabolic signal indicating that further glucose oxidation is unnecessary, and that glucogenic precursors should be directed toward glucose synthesis and storage