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Despite distinct enzymatic defects (MMUT versus propionyl-CoA carboxylase deficiency), both disorders exhibit neurological sequelae, including seizures, developmental delay, and structural brain abnormalities (Ballhausen et al

Wang X, Tay SSW, Ng YK

3 Indeed, some have suggested that the systemic abnormalities in ASD such as mitochondrial dysfunction may arise from environmental triggers 7 in genetically sensitive subpopulations

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