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Glutamate can then be further catalyzed by glutamate dehydrogenase 1 (GDH1) to generate A-ketoglutarate (A-KG), thereby driving glutaminolysis

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Since L-carnosine and zinc each have mucosa-supportive properties, it is not surprising that the zinc L-carnosine ligand significantly protects and has been shown to enhance the integrity of the gastric lining