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In clinical trials with somatropin in GHD adults, the majority of the adverse events consisted of mild to moderate symptoms of fluid retention, including peripheral swelling, arthralgia, pain and stiffness of the extremities, peripheral edema, myalgia, paresthesia, and hypoesthesia

Laboratory and animal research suggests that MOTS-c participates in cellular responses to metabolic stress

In a supplementary analysis, both light-logging devices demonstrated strong correlations with each other and with calibrated light sources, suggesting that potential confounding effects due to device differences are likely minimal (Fig

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