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Chemotherapy is also reported to induce cognitive impairments, associated with the alteration of white matter integrity

A recent review found that creatine supplements are effective and safe, even when taken for long periods or in large doses

110 Treatment with 1,500 mg curcumin per day for 12 weeks was also shown to upregulate expression of a PPAR- activator molecule and improve markers of oxidative stress more than placebo in a controlled trial in 72 women with PCOS